Key result
Metabolic syndrome in hypertensive patients was associated with a higher prevalence of left ventricular hypertrophy (57.7% vs 25.1%, P<0.00001), microalbuminuria, and hypertensive retinopathy.
Why the study?
Does the presence of metabolic syndrome amplify hypertension-related target organ damage in essential hypertensive patients without diabetes?
Population
353 young and middle-aged essential hypertensive patients without diabetes mellitus, free from…
Comparison
Presence of metabolic syndrome vs Absence of metabolic syndrome
Design
Cross-sectional
Authors
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May identify hypertensives needing intensified monitoring; leaves open whether metabolic syndrome treatment reduces target organ damage.
Cross-Sectional (n=353)
Does the presence of metabolic syndrome amplify hypertension-related target organ damage in essential hypertensive patients without diabetes?
Absolute Event Rate: 57.7% vs 25.1%
p-value: p=<0.00001
Metabolic syndrome significantly amplifies preclinical cardiac, renal, and retinal damage in essential hypertensive patients, independent of individual components.
Mulè et al. (2005) conducted a cross-sectional in Essential hypertension (n=353). Metabolic syndrome vs. Without metabolic syndrome was evaluated on Left ventricular hypertrophy (p=<0.00001). Metabolic syndrome in hypertensive patients was associated with a higher prevalence of left ventricular hypertrophy (57.7% vs 25.1%, P<0.00001), microalbuminuria, and hypertensive retinopathy.
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