Why the study?
Does oxprenolol improve blood pressure control and fetal outcomes compared to methyldopa in pregnant women with hypertension?
Population
100 pregnant women with hypertension, stratified into early and late entry, compared with nonhypertensive…
Comparison
Oxprenolol vs Methyldopa
Design
RCT, Allocated at random, stratified by early and late gestation entry
Follow-up
Until delivery
Authors
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Oxprenolol offers a viable alternative to methyldopa in pregnancy hypertension; confirms comparable fetal safety in this RCT.
Does oxprenolol improve blood pressure control and fetal outcomes compared to methyldopa in pregnant women with hypertension?
Oxprenolol and methyldopa result in similar fetal outcomes when used for hypertension in pregnancy, though oxprenolol may require more dose increments for blood pressure control in early-onset cases.
Fidler et al. (1983) studied this question.
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