January 1, 2001Critical Care Medicine

α-Atrial natriuretic peptide, cyclic guanosine monophosphate, and endothelin in plasma as markers of myocardial depression in human septic shock

View Full Paper

Ask AI

Bookmark

Population

14 consecutive patients with septic shock and arterial and pulmonary artery catheters in place, admitted to…

Design

Cohort

Follow-up

3 days

Authors

KHKoen J. HarteminkLeiden University AGA. B. Johan GroeneveldCARE USA MGMarcel C. M. de GrootVrije Universiteit Amsterdam

Discussion

Member takes

Implication

May flag myocardial depression in septic shock; hypothesis-generating and should not yet change practice.

Structured PICO

Population

14 consecutive patients with septic shock and arterial and pulmonary artery catheters in place, admitted to a medical intensive care unit of a university hospital.

Outcome

Myocardial depression (defined as left ventricular stroke work index [LVSWI] < 35 g/m2) and its association with plasma levels of alpha-ANP, cGMP, and endothelin.surrogate

Circulating alpha-ANP, endothelin, and particularly cGMP may serve as markers for myocardial depression in patients with septic shock.

Cite This Study

Hartemink et al. (2001) studied this question.

synapsesocial.com/papers/6a707caf8031ec7bb1dc6059 https://doi.org/10.1097/00003246-200101000-00019

Topics

Cardiomyopathy

View Full Paper

Ask AI

Bookmark

α-Atrial natriuretic peptide, cyclic guanosine monophosphate, and endothelin in plasma as markers of myocardial depression in human septic shock

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

α-Atrial natriuretic peptide, cyclic guanosine monophosphate, and endothelin in plasma as markers of myocardial depression in human septic shock

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider