Why the study?
Does plasma brain natriuretic peptide level correlate with systolic myocardial dysfunction and mortality in patients with severe sepsis or septic shock?
Population
34 consecutive patients with severe sepsis or septic shock without previous cardiac, respiratory, or chronic…
Comparison
Measurement of plasma brain natriuretic peptide… vs Patients without myocardial dysfunction and ICU…
Design
Cohort
Follow-up
28 days
Authors
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BNP may flag myocardial dysfunction and ICU mortality risk in sepsis; leaves open whether monitoring alters management.
Does plasma brain natriuretic peptide level correlate with systolic myocardial dysfunction and mortality in patients with severe sepsis or septic shock?
Elevated plasma BNP levels in patients with severe sepsis or septic shock are associated with systolic myocardial dysfunction and increased ICU mortality.
Charpentier et al. (2004) studied this question.
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