Key result
B-type natriuretic peptide concentrations were elevated on admission (747 +/- 860 pg/mL) in severe sepsis and septic shock but did not predict in-hospital mortality or length of stay.
Why the study?
Does B-type natriuretic peptide predict in-hospital mortality and length of stay in patients with severe sepsis or septic shock?
Observational (n=40)
Does B-type natriuretic peptide predict in-hospital mortality and length of stay in patients with severe sepsis or septic shock?
B-type natriuretic peptide is elevated in severe sepsis and septic shock regardless of cardiac dysfunction, but it does not provide prognostic value for in-hospital mortality or length of stay.
Answers are grounded in this paper and cite their sources.
BNP lacks prognostic value in severe sepsis; leaves open whether alternative biomarkers improve risk stratification in critical care.
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McLean et al. (2007) conducted an observational in Severe sepsis and septic shock (n=40). B-type natriuretic peptide (BNP) measurement was evaluated on In-hospital mortality and length of stay. B-type natriuretic peptide concentrations were elevated on admission (747 +/- 860 pg/mL) in severe sepsis and septic shock but did not predict in-hospital mortality or length of stay.
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