Why the study?
The beneficial effects of regular exercise training in cardiovascular disease remain partly unexplained, and platelets may be affected by regular exercise training.
Does regular exercise training affect platelet function in patients with cardiovascular disease and healthy individuals?
Does regular exercise training affect platelet function in patients with cardiovascular disease and healthy individuals?
A systematic review found no clear impact of regular exercise training on platelet function in patients with CVD or healthy individuals.
Answers are grounded in this paper and cite their sources.
Regular exercise training benefits in CVD appear independent of platelet effects; challenges assumptions and leaves mechanisms for further study.
INTRODUCTION: Regular exercise training is essential in prevention and treatment of cardiovascular disease (CVD), yet the beneficial effects of exercise remain only partly explained. Platelets play a key role in CVD and may be affected by regular exercise training. We aimed to systematically summarise studies investigating the effect of regular exercise training on platelet function in patients with CVD and in healthy individuals. METHODS: Studies were identified by PubMed, Embase and Web of Science May 16, 2022. We selected studies investigating markers of platelet function in relation to regular exercise training in patients with CVD and in healthy individuals. Regular exercise was defined as exercise training for four weeks or more. There were no between-group differences in the seven studies examining soluble P-selectin. CONCLUSION: Regular exercise training has no clear impact on platelet function in patients with CVD or healthy individuals. PROSPERO REGISTRATION: CRD42022350539.
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Kristiansen et al. (2022) studied this question.
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