Why the study?
Does treadmill exercise increase shear-induced platelet aggregation in patients with effort angina?
Does treadmill exercise increase shear-induced platelet aggregation in patients with effort angina?
Treadmill exercise increases shear-induced platelet aggregation in patients with effort angina, a mechanism likely dependent on increased von Willebrand factor larger multimers rather than platelet alpha2-receptor activation.
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Exercise may heighten thrombotic risk in effort angina; leaves open vWF multimers as a target for prospective trials.
Tokuue et al. (1996) studied this question.
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