October 25, 2013HaematologicaOpen Access

Distinct frequencies and mutation spectrums of genetic thrombophilia in Korea in comparison with other Asian countries both in patients with thromboembolism and in the general population

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Population

500 consecutive patients with venous thromboembolism and 3,129 individuals from the general population…

Design

Cross-sectional

Authors

HKH.-J. Kim JSJ.-Y. Seo KLK.-O. Lee

Discussion

Member takes

Implication

May support ethnicity-specific thrombophilia evaluation in Korean VTE; leaves open prospective validation of mutation prevalence.

Structured PICO

Population

500 consecutive patients with venous thromboembolism (VTE) and 3,129 individuals from the general population undergoing routine check-ups in Korea.

Outcome

Frequency and mutation spectrums of natural anticoagulant (protein C, protein S, antithrombin) deficiencies.surrogate

The frequency and mutation spectrum of genetic thrombophilia in Korea differ significantly from those in Caucasian and other Asian populations, with a high prevalence of specific antithrombin and protein C mutations.

Cite This Study

Kim et al. (2013) studied this question.

synapsesocial.com/papers/6a70811326a7f98052dcffef https://doi.org/10.3324/haematol.2013.092023

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Distinct frequencies and mutation spectrums of genetic thrombophilia in Korea in comparison with other Asian countries both in patients with thromboembolism and in the general population

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Distinct frequencies and mutation spectrums of genetic thrombophilia in Korea in comparison with other Asian countries both in patients with thromboembolism and in the general population

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider