Why the study?
Does elevated circulating Angiopoietin-2 predict adverse renal outcomes in patients with stages 3-5 CKD?
Population
621 patients with stages 3-5 chronic kidney disease, mean age 65.3, 55.4% male, from a tertiary hospital in…
Comparison
Elevated circulating Angiopoietin-2 levels vs Lowest quartile of circulating Angiopoietin-2…
Design
Cohort
Follow-up
mean 38.2 months
Authors
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Elevated Angiopoietin-2 may aid prognostication in stages 3-5 CKD; hypothesis-generating for targeted therapies pending confirmatory trials.
Does elevated circulating Angiopoietin-2 predict adverse renal outcomes in patients with stages 3-5 CKD?
Elevated circulating Angiopoietin-2 is an independent predictor of adverse renal outcomes, including commencing dialysis and rapid eGFR decline, in patients with stages 3-5 CKD.
Tsai et al. (2014) studied this question.
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