Why the study?
Does grape seed proanthocyanidins extract reduce reperfusion arrhythmia in rabbit models of cardiac ischemic reperfusion injury?
Population
Rabbit models of cardiac ischemic reperfusion injury
Comparison
Grape seed proanthocyanidins extracts 100 mg/kg… vs Model control group
Design
Preclinical
Follow-up
3 weeks
Authors
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GSPE merits further preclinical testing in ischemia-reperfusion; leaves open translation to human reperfusion arrhythmias.
Does grape seed proanthocyanidins extract reduce reperfusion arrhythmia in rabbit models of cardiac ischemic reperfusion injury?
Grape seed proanthocyanidins extracts protect against myocardial ischemic reperfusion arrhythmias in a rabbit model, likely by preserving connexin 43 and gap junctions.
Liang et al. (2009) studied this question.
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