What question did this study set out to answer?

To assess the therapeutic effect of treating comorbid reflux esophagitis with a proton pump inhibitor on paroxysmal atrial fibrillation episodes.

June 1, 2007Open Access

Case of paroxysmal atrial fibrillation improved after the administration of proton pump inhibitor for associated reflux esophagitis.

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Why the study?

Does rabeprazole reduce paroxysms of atrial fibrillation in a patient with concurrent reflux esophagitis?

Population

1 adult male with paroxysmal atrial fibrillation and reflux esophagitis, with limited response to…

Design

Case_report

Authors

HNHirofumi NakamuraKyoto University GNGen NakajiKyushu University HSHideki ShimazuMukogawa Women's University

Discussion

Member takes

Implication

May reduce AF paroxysms when treating concurrent reflux esophagitis; leaves open causality and generalizability beyond this case.

Key Points

To assess the therapeutic effect of treating comorbid reflux esophagitis with a proton pump inhibitor on paroxysmal atrial fibrillation episodes.
Evaluated a 64-year-old male presenting with paroxysmal atrial fibrillation confirmed by ambulatory electrocardiographic monitoring and reflux esophagitis confirmed by endoscopy.
Administered the proton pump inhibitor rabeprazole (10 mg/day) following inadequate arrhythmia control with the antiarrhythmic agent disopyramide (300 mg/day).
Proton pump inhibitor therapy produced marked subjective and endoscopic resolution of reflux esophagitis.
Episodes of paroxysmal atrial fibrillation were markedly reduced following proton pump inhibitor administration.

Structured PICO

Does rabeprazole reduce paroxysms of atrial fibrillation in a patient with concurrent reflux esophagitis?

Population

1 adult male (64 years old) with paroxysmal atrial fibrillation and reflux esophagitis, with limited response to disopyramide 300 mg/day.

Intervention

Rabeprazole 10 mg/day (proton pump inhibitor)

Outcome

Reduction in paroxysms of atrial fibrillation and improvement of reflux esophagitis

Treatment of reflux esophagitis with a proton pump inhibitor may reduce paroxysms of atrial fibrillation in patients with both conditions.

Cite This Study

Nakamura et al. (2007) studied this question.

synapsesocial.com/papers/6a7089a2a7fbea1e44081d07 https://doi.org/10.15017/6201

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Case of paroxysmal atrial fibrillation improved after the administration of proton pump inhibitor for associated reflux esophagitis.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Case of paroxysmal atrial fibrillation improved after the administration of proton pump inhibitor for associated reflux esophagitis.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

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