Why the study?
Do global and regional longitudinal deformation parameters during the early recovery phase after DSE improve the prediction of significant coronary artery stenosis compared to conventional visual assessment in patients with stable CAD?
Do global and regional longitudinal deformation parameters during the early recovery phase after DSE improve the prediction of significant coronary artery stenosis compared to conventional visual assessment in patients with stable CAD?
Recovery-phase LS/SR may enhance DSE ischemia detection; leaves open incremental value over peak stress in larger studies.
Introduction: Global and regional longitudinal deformation parameters are feasible and reproducible during all stages of dobutamine speckle tracking echocardiography (DSE). However, still little is known about the diagnostic value of longitudinal strain (LS)/strain rate (SR) parameters during recovery phase of DSE, while their role can be substantial. Purpose: To compare the diagnostic value of global and regional longitudinal deformation parameters during early recovery phase after DSE and conventional visual assessment of wall motion abnormalities (WMA) to predict significant coronary artery (CA) stenosis in patients (pt) with stable coronary artery disease (CAD). Methods: DSE and adenosine magnetic resonance imaging (AMRI) were perfomed to 148 pt with stable CAD. CAD was defined as >75% diameter CA stenosis on invasive angiography or in the presence of intermediate stenosis (50–75%) validated as hemodynamically significant by AMRI. Global and regional peak LS and peak systolic SR were analysed using 2D speckle tracking echocardiography (STE) during early recovery phase after DSE. Patients were divided into two groups: non-obstructive CAD (-) n=82 (55.4%) vs obstructive CAD (+) n=66 (44.6%).
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Rumbinaitė et al. (2017) studied this question.
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