Why the study?
Does a single pericardiocentesis followed by intensive systemic combination chemotherapy prevent the need for reaspiration in patients with malignant pericardial effusion due to metastatic breast carcinoma?
Population
3 patients with metastatic carcinoma of the breast and malignant pericardial effusion
Design
Case_series
Authors
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May support conservative management in select breast cancer cases; hypothesis-generating and should not yet change practice.
Does a single pericardiocentesis followed by intensive systemic combination chemotherapy prevent the need for reaspiration in patients with malignant pericardial effusion due to metastatic breast carcinoma?
A single pericardiocentesis followed by systemic chemotherapy may be an effective conservative initial approach for managing malignant pericardial effusion in breast cancer.
Reynolds et al. (1977) studied this question.