Why the study?
Does trimetazidine monotherapy improve left ventricular function in patients with stable angina pectoris?
Population
Patients with stable angina pectoris from 11 randomized controlled trials.
Comparison
Trimetazidine monotherapy for at least 2 weeks. vs Placebo.
Design
Meta-analysis
Follow-up
at least 2 weeks
Authors
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Supports trimetazidine to improve LV function in stable angina; strengthens pooled RCT evidence for its use.
Does trimetazidine monotherapy improve left ventricular function in patients with stable angina pectoris?
Trimetazidine monotherapy significantly improves left ventricular ejection fraction and reduces end-systolic volume in patients with stable angina pectoris.
Hu et al. (2011) studied this question.
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