Why the study?
Does trimetazidine reduce angina attacks and improve exercise parameters in patients with stable angina pectoris?
Population
Patients with stable angina pectoris from 12 double-blind, randomized, controlled trials.
Comparison
Trimetazidine in monotherapy or in combination… vs Placebo or conventional antianginal agent
Design
Meta-analysis, randomized, double-blind
Follow-up
at least 2 weeks
Authors
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Supports trimetazidine for symptom control in stable angina; confirms efficacy as monotherapy and add-on.
Does trimetazidine reduce angina attacks and improve exercise parameters in patients with stable angina pectoris?
Trimetazidine effectively reduces angina frequency and improves exercise tolerance in patients with stable angina, both as monotherapy and add-on therapy.
Marzilli et al. (2003) studied this question.
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