Why the study?
Does the urinary proteomic biomarker CKD273 predict a decline of eGFR to <60 ml/min per 1.73 m2 in individuals with baseline eGFR ≥ 60 ml/min per 1.73 m2?
Does the urinary proteomic biomarker CKD273 predict a decline of eGFR to <60 ml/min per 1.73 m2 in individuals with baseline eGFR ≥ 60 ml/min per 1.73 m2?
The urinary proteomic biomarker CKD273 adds incremental value to baseline eGFR and albuminuria in predicting the onset of stage 3 chronic kidney disease.
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CKD273 may flag incident CKD risk in preserved eGFR; leaves open clinical adoption pending prospective validation.
Pontillo et al. (2017) studied this question.
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