Transmural, haemorrhagic myocardial infarction after intracoronary streptokinase. Clinical, angiographic, and necropsy findings.
Population
6 patients who died in cardiogenic shock 1 to 18 days after intracoronary thrombolysis, out of a cohort of…
Design
Case_series
Follow-up
1 to 18 days
Authors
Discussion
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Member takes
Implication
Alerts to hemorrhagic infarction risk despite early recanalization; leaves open safety of intracoronary streptokinase in acute MI.
Structured PICO
P
Population
6 patients who died in cardiogenic shock 1 to 18 days after intracoronary thrombolysis, out of a cohort of 101 patients with acute myocardial infarction whose coronary arteries were successfully recanalised.
I
Intervention
Intracoronary streptokinase (average 200,000 units)
O
Outcome
Clinical, angiographic, and necropsy findings (infarct type, size, and vessel patency)hard clinical
Intracoronary streptokinase for acute MI can lead to large, haemorrhagic transmural infarctions despite successful recanalisation, particularly in early LAD occlusions.
Cite This Study
Mathey et al. (1982) studied this question.