Why the study?
Does intracoronary administration of adenosine increase coronary blood flow in conscious patients with normal coronary angiograms?
Population
n=6 conscious patients with normal coronary angiograms and normal ventricular function
Comparison
Intracoronary bolus injections of 0.1, 0.5, 1.0… vs Baseline (control flow)
Design
Case_series
Authors
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May support adenosine for coronary flow assessment in conscious patients; leaves open validation in larger cohorts.
Does intracoronary administration of adenosine increase coronary blood flow in conscious patients with normal coronary angiograms?
Intracoronary adenosine safely produces a dose-dependent increase in regional and total coronary blood flow in conscious humans.
Marzilli et al. (1989) studied this question.
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