Why the study?
Are IL-6 promoter polymorphisms associated with hyperandrogenism in women?
Are IL-6 promoter polymorphisms associated with hyperandrogenism in women?
The -597G-->A and -174G-->C polymorphisms in the IL-6 gene promoter are associated with hyperandrogenism and higher circulating levels of IL-6 and adrenal steroids.
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IL-6 promoter haplotypes were associated with hyperandrogenism; hypothesis-generating and requires replication before any clinical consideration.
Villuendas et al. (2002) studied this question.
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