Why the study?
Does the G allele at position -174 of the IL-6 gene increase fasting and postglucose load plasma lipids in healthy subjects compared to the C allele?
Population
Healthy subjects
Comparison
G allele at position -174 of the IL-6 gene vs Carriers of the C allele at position -174 of the…
Design
Cross-sectional
Authors
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IL-6 -174G may link to higher lipid levels in healthy adults; hypothesis-generating and should not yet change practice.
Does the G allele at position -174 of the IL-6 gene increase fasting and postglucose load plasma lipids in healthy subjects compared to the C allele?
The -174G polymorphism in the IL-6 gene is associated with higher fasting and post-load plasma lipids in healthy subjects, suggesting a genetic predisposition to lipid abnormalities.
Fernández‐Real et al. (2000) studied this question.
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