Why the study?
Does the IL-6 gene polymorphism at position -174 influence insulin sensitivity and postload glucose levels?
Population
Subjects evaluated for IL-6 gene polymorphism and insulin sensitivity
Comparison
Homozygous for the C allele at position -174 of… vs Carriers of the G allele (C/G and G/G individuals)
Design
Cross-sectional
Authors
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IL-6 -174 C/C genotype was associated with better insulin sensitivity; leaves open prospective role in diabetes risk stratification.
Does the IL-6 gene polymorphism at position -174 influence insulin sensitivity and postload glucose levels?
The IL-6 gene polymorphism at position -174 is associated with differences in insulin sensitivity and postload glucose levels, supporting a link between acute-phase response and insulin resistance.
Fernández‐Real et al. (2000) studied this question.
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