What question did this study set out to answer?

The research aims to understand haemodynamic responses to head-up tilt in young versus elderly subjects under different thermal conditions.

May 1, 1998Clinical Science

Haemodynamic Responses in Young and Elderly, Healthy Subjects during Ambient and Warm Head-up Tilt

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Why the study?

Does passive body warming alter haemodynamic responses to head-up tilt in healthy young and elderly subjects?

Key Points

The research aims to understand haemodynamic responses to head-up tilt in young versus elderly subjects under different thermal conditions.
Nine young (mean age 28.7 years) and nine elderly (mean age 71.9 years) healthy subjects underwent head-up tilt testing.
Subjects were monitored for haemodynamic responses at ambient temperature and after being covered with blankets to induce passive heating.
Skin temperature was measured before and during the second tilt to assess changes.
Elderly subjects exhibited consistently higher blood pressures during both tilts (P < 0.001).
Young subjects demonstrated greater changes in stroke volume and cardiac indices during head-up tilts compared to elderly (P < 0.01).
Both age groups displayed similar qualitative responses to tilt, suggesting maintained reflexes despite body warming.

Structured PICO

Does passive body warming alter haemodynamic responses to head-up tilt in healthy young and elderly subjects?

Population

18 healthy subjects, comprising 9 young (mean age 28.7 +/- 1.5 years) and 9 elderly (mean age 71.9 +/- 1.8 years), carefully screened to exclude cardiovascular pathology.

Intervention

Head-up tilt with passive heating (covered in blankets for 55 min, increasing skin temperature to approximately 35.2 degrees C).

Comparator

Standard head-up tilt at ambient room temperature (skin temperature approximately 32.5 degrees C).

Outcome

Haemodynamic responses (blood pressure, heart rate, stroke volume, and cardiac index) to head-up tilt.surrogate

Short-term natural body warming does not impair haemodynamic reflexes to head-up tilt in healthy young or elderly subjects.

Discussion

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Implication

Supports preserved orthostatic reflexes with mild warming in healthy adults; leaves open relevance to patients with autonomic impairment or prolonged heat.

Cite This Study

Lye et al. (1998) studied this question.

synapsesocial.com/papers/6a70989184cc45bb7bdfcba5 https://doi.org/10.1042/cs0940493

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Implication

Supports preserved orthostatic reflexes with mild warming in healthy adults; leaves open relevance to patients with autonomic impairment or prolonged heat.

Haemodynamic Responses in Young and Elderly, Healthy Subjects during Ambient and Warm Head-up Tilt

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Haemodynamic Responses in Young and Elderly, Healthy Subjects during Ambient and Warm Head-up Tilt

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider