March 21, 2008Catheterization and Cardiovascular Interventions
Percutaneous implantation of the first repositionable aortic valve prosthesis in a patient with severe aortic stenosis
Why the study?
Does the Lotus Valve prosthesis improve hemodynamics and symptoms in a high-risk patient with severe aortic stenosis?
Population
1 patient with severe symptomatic aortic stenosis who was declined for surgical valve replacement due to…
Design
Case_report
Follow-up
3 months
Authors
Discussion
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Member takes
Implication
Supports Lotus Valve feasibility in high-risk severe AS; leaves open durability, safety, and efficacy confirmation in prospective trials.
Structured PICO
Does the Lotus Valve prosthesis improve hemodynamics and symptoms in a high-risk patient with severe aortic stenosis?
P
Population
1 patient (93-year old) with severe symptomatic aortic stenosis (valve area: 0.6 cm2) who was declined for surgical valve replacement due to comorbidities.
I
Intervention
Percutaneous implantation of the self-expanding, repositionable Lotus Valve prosthesis (nitinol frame with bovine pericardial leaflets) via retrograde approach.
O
Outcome
Successful insertion and deployment, reduction of transaortic mean pressure gradient, final valve area, residual aortic regurgitation, and clinical status (NYHA class).surrogate
First-in-man experience demonstrates the feasibility and short-term efficacy of percutaneous implantation of the repositionable Lotus Valve in a high-risk patient with severe aortic stenosis.
Limitations
- Further studies are mandatory to assess device safety and efficacy in larger patient populations.
Cite This Study
Buellesfeld et al. (2008) studied this question.