Population
Isolated rat neonatal myocytes loaded with the Ca(2+)-sensitive fluorescent dye fluo 3
Design
Preclinical
Authors
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Characterizes spontaneous Ca2+ release patterns in neonatal rat myocytes; leaves open relevance to adult human arrhythmias.
Spontaneous Ca2+ release in neonatal rat cardiac myocytes exhibits distinct subcellular patterns that are likely modulated locally by the Ca2+-loading state of individual sarcoplasmic reticulum elements.
Lipp et al. (1994) studied this question.
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