Population
Isolated mammalian cardiac myocytes prepared by perfusion of adult rabbit hearts with…
Comparison
Computerized image-analysis techniques and… vs Records of whole-cell shortening and of…
Design
Preclinical
Authors
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Supports regenerative CICR in isolated myocytes; leaves open relevance to intact myocardium or clinical arrhythmias.
Computerized image analysis demonstrates that sarcomere shortening in isolated cardiac myocytes propagates longitudinally, supporting a regenerative mechanism of calcium-induced calcium release.
Rieser et al. (1979) studied this question.
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