Why the study?
Does oral acebutolol reduce or prevent cardiac arrhythmias in ambulatory patients with heart disease?
Does oral acebutolol reduce or prevent cardiac arrhythmias in ambulatory patients with heart disease?
In a preliminary report, short-term oral acebutolol demonstrated efficacy in preventing or improving cardiac arrhythmias in ambulatory patients.
A study was carried out in 20 ambulatory patients with various heart diseases and different forms of cardiac arrhythmias to evaluate the anti-arrhythmic effect of acebutolol when given orally(400 mg/day). Long-term(4 hour) ECGs were monitored before and after 3 days of treatment. The results showed that after acebutolol treatment 60% of all the arrhythmias were prevented or abolised, 16% were improved, and only 24% persisted unchanged.
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Burckhardt et al. (1977) studied this question.
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