Why the study?
Clinical outcome of AVR strongly depends on implanted prosthetic valve size, but the effect of valve size on bioprosthetic valve hemodynamics needed investigation to optimize surgical outcomes.
Does larger bioprosthetic valve size improve hemodynamic performance in fluid-structure interaction models of aortic valve replacement?
Does larger bioprosthetic valve size improve hemodynamic performance in fluid-structure interaction models of aortic valve replacement?
Computational fluid-structure interaction modeling suggests that implanting larger bioprosthetic valves during aortic valve replacement significantly improves hemodynamic performance by reducing transvalvular pressure gradients and flow shear stress.
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FSI models may guide AVR valve sizing for better hemodynamics; leaves open prospective clinical validation before practice change.
Li et al. (2021) studied this question.
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