Why the study?
Does hypothermia and hypercapnia alter coronary arteriovenous electrolyte differences and induce ventricular fibrillation in dogs?
Population
26 dogs (normo- and hypercapneic)
Comparison
Cooling to 24 C with or without hypercapnia vs Normal temperature
Design
Preclinical
Authors
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Electrolyte shifts may trigger hypothermic VF under hypercapnia in dogs; leaves open relevance to clinical cooling.
Does hypothermia and hypercapnia alter coronary arteriovenous electrolyte differences and induce ventricular fibrillation in dogs?
Hypothermic ventricular fibrillation in hypercapneic dogs is associated with myocardial gain of calcium and loss of potassium and hydrogen ions.
Covino et al. (1955) studied this question.
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