This review highlights that isolated systolic hypertension in the elderly is a distinct pathophysiological entity driven by arterial stiffness, where increased pulse pressure is a major cardiovascular risk factor that warrants treatment.
Answers are grounded in this paper and cite their sources.
Supports treating isolated systolic hypertension in elderly without clear J-curve harm; leaves open optimal diastolic targets for prospective trials.
Once considered an inconsequential part of the aging process, the development of isolated systolic hypertension represents a late manifestation of increased elastic artery stiffness and is the predominant hypertensive subtype in the middle-aged and elderly populations. Its inherent increased risk for vascular events, such as coronary heart disease, stroke, heart failure, peripheral artery disease, chronic kidney disease, and dementia, highlights the importance of its control. The purpose of this short review is to summarize how hypertension is different in the elderly when compared with "essential hypertension" in younger adults. The emphasis will be on the multiple ways that increased artery stiffness affects the natural history and clinical manifestations of hypertension in the elderly.
No takes yet. Share an insight, caveat, or question.
Stanley S. Franklin (2012) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: