Night-time blood pressure
Why the study?
Does a diminished nocturnal blood pressure fall (non-dipping) increase the risk of cardiovascular mortality?
Population
1,542 inhabitants of Ohasama, Japan
Comparison
Diminished nocturnal blood pressure fall vs Normal nocturnal blood pressure fall
Design
Editorial
Follow-up
9.2 years
Authors
Discussion
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Member takes
Implication
Nocturnal hypertension and a non-dipping blood pressure profile are independent risk factors for cardiovascular mortality, highlighting the clinical importance of 24-hour ambulatory blood pressure monitoring.
Structured PICO
Does a diminished nocturnal blood pressure fall (non-dipping) increase the risk of cardiovascular mortality?
P
Population
1,542 inhabitants of Ohasama, Japan
I
Intervention
Diminished nocturnal blood pressure fall (non-dipping pattern, defined as nocturnal decline <10%)
C
Comparator
Normal nocturnal blood pressure fall (dipping pattern)
O
Outcome
Cardiovascular mortalityhard clinical
Nocturnal hypertension and a non-dipping blood pressure profile are independent risk factors for cardiovascular mortality, highlighting the clinical importance of 24-hour ambulatory blood pressure monitoring.
Limitations
- Lack of standardization
- Arbitrary dichotomization of a continuous measurement
- Inappropriate selection of cases and controls
- Failure to account for confounding issues
- Poor reproducibility of the night-to-day ratio and regression-to-the-mean phenomenon
Cite This Study
Stolarz et al. (2002) studied this question.