Why the study?
Time-varying electromagnetic fields can be induced when myocardial cells are exposed to electromagnetic fields, requiring consideration of electromagnetic induction effects on electrical activities.
Computational modeling demonstrates that mixed frequencies magnetic radiation can modulate myocardial cell electrical activity, inducing bursting or quiescent states depending on radiation parameters.
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May induce mode transitions in myocardial models; leaves open clinical relevance of electromagnetic induction.
Based on the standard Fitzhugh-Nagumo model for myocardial cell excitations and electrical activities, the effect of electromagnetic induction is considered and through which mixed frequencies magnetic radiation is imposed to detect the mode transition. Indeed, time-varying electromagnetic field can be induced when myocardial cell is exposed or surrounded by electromagnetic field and thus the effect of electromagnetic induction should be considered. From the analyzes of sampled series for membrane potentials, the improved model holds many bifurcation parameters and the mode of excitations and electric activities can be detected and observed in larger parameter zones. It is found that apart from exciting a myocardial cell, the mixed frequencies magnetic radiation can promote mode transition to bursting type behavior as the frequency is increased as well as suppress the electrical activities to quiescent state under high intensities magnetic radiations, which are consistent with biological experiments.
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Takembo et al. (2022) studied this question.
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