Why the study?
Do cerebral protection devices prevent neurologic events in patients undergoing TAVI?
Do cerebral protection devices prevent neurologic events in patients undergoing TAVI?
This review highlights the technical feasibility of cerebral protection devices during TAVI, emphasizing the need for larger trials to confirm their efficacy in stroke prevention.
Early feasibility of cerebral protection devices in TAVI warrants clinical caution; larger trials are needed to determine neurologic benefit.
Ever since the publication of the PARTNER trials, the spotlight has turned to neurologic events during transcatheter aortic valve i mplantation ( TAVI). Recently published long-term follow-up data mitigated the initial concerns, however, stroke prevention during TAVI remains an important issue. This review article focuses on the currently available cerebral protection devices for TAVI and puts them in perspective of the overall “stroke issue”. Cerebral protection devices either deflect emboli (Embrella, EDD) or capture them (Claret, EmbolX). In TAVI, only first-in-human studies with those devices are currently published, with all of them showing technical feasibility. Larger trials are underway and will shed light on the role of cerebral protection devices during TAVI and their clinical impact on preventing neurologic events.
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F. Nietlispach (2012) studied this question.
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