Why the study?
Does combined carotid endarterectomy and cardiac surgery prevent perioperative stroke in patients with coexisting severe cardiac and carotid disease?
Does combined carotid endarterectomy and cardiac surgery prevent perioperative stroke in patients with coexisting severe cardiac and carotid disease?
Combined carotid endarterectomy immediately before cardiopulmonary bypass is a safe approach that may minimize perioperative stroke risk in patients with coexisting severe cardiac and carotid disease.
No strokes seen in this series; hypothesis-generating for combined CEA-cardiac surgery but should not change practice without controlled trials.
Severe cerebrovascular complications following cardiac surgical procedures remain a major concern, particularly in patients with significant carotid atherosclerotic involvement (14% of perioperative stroke). Operative mortality for carotid operations in patients with documented Coronary Artery Disease (CAD) may be as high as 20%. Seventy patients underwent combined operations (unilateral carotid stenosis > 70%, unilateral stenosis > 50% with ulcerated plaque or bilateral stenoses > 50%; and this also included patients with unilateral occlusion). Cardiac procedures were 69 coronary artery bypass grafts, four left ventricular aneurysmectomies, three aortic valve replacements and surgery on two mitral valves. Seven perioperative deaths occurred, which were all caused by cardiac events. There were no perioperative strokes. Carotid endarterectomy immediately before cardiopulmonary bypass is a safe and expeditious approach to coexisting significant cardiac and carotid disease. In our experience, technical details in monitoring and minimizing cerebral ischemia are possibly more crucial in these severe vasculopathic patients. Moreover, it is probably advantageous from an economic standpoint compared with other therapeutic treatments.
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Francesco Donatelli (1998) studied this question.
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