This case report documents an extremely rare presentation of Infantile Hemangioendothelioma in the head and neck region.
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Alerts clinicians to infantile hemangioendothelioma in the lower lip; extends reported sites but leaves management questions open.
Correspondence: Köksal Yuca, MD, Yüzüncü Yıl University, Faculty of Medicine, Department of Otorhinolaryngology, 65200, Van-Turkey Tel: 904322157168, Fax: 904322166563 E-mail: koksalyuca@yahoo.com INTRODUCTION Infantile hemangioendothelioma(IHE) is a severe disease with a high mortality. It is characterized by multiple hemangiomas affecting the skin and visceral organs (1). Hemangioendothelioma is a rare vascular tumor of endothelial cell origin show an intermediate malignant potential between simple hemangioma and angiosarcoma. The tumor is characterized by neoplastic proliferation of epitheloid or histiocytic endothelial cells. It may involve bone or soft tissues of extremities and can behave like a benign or malignant tumor. The occurrence in the head and neck region is a rare and believed to be a neoplasm of borderline malignancy. In the literature, there are several case reports on the involvement of the head and neck region (2-5). For primary treatment recommendation there is general agreement in the literature as surgical excision of the tumor (2-4, 6). We reported a case of a 4-month old infant with IHE resulted in soft tissue destruction of lover lip and histologic findings were described.
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Yuca et al. (2005) studied this question.
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