Why the study?
Does mirtazapine prolong the QTc interval compared to placebo?
Comparison
Mirtazapine at 45-mg and 75-mg doses vs Placebo
Design
Other
Authors
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May inform mirtazapine prescribing in arrhythmia-prone patients; leaves open need for larger confirmatory QT studies.
Does mirtazapine prolong the QTc interval compared to placebo?
Mirtazapine at 45-mg and 75-mg doses causes a concentration-dependent but not clinically meaningful prolongation of the QTc interval.
Gurkan et al. (2018) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: