September 14, 2004Circulation

Endothelial Dysfunction and Damage in Congestive Heart Failure

View Full Paper

Ask AI

Bookmark

Population

30 patients with congestive heart failure (CHF) and 20 age-matched control subjects (total n=50)

Design

Case-control

Authors

ACAun‐Yeong ChongUniversity of Ottawa ABAndrew D. BlannVascular Medicine JPJeetesh V. PatelNational Health Service

Discussion

Member takes

Implication

May refine CHF prognostication beyond BNP; hypothesis-generating and requires prospective validation.

Structured PICO

Population

30 patients with congestive heart failure (CHF) and 20 age-matched control subjects (total n=50)

Comparator

20 age-matched control subjects

Outcome

Endothelial perturbation (defined by flow-mediated endothelial-dependent vasodilation [FMD], circulating endothelial cells [CECs], von Willebrand factor [vWf], and soluble thrombomodulin [sTM]) and brain natriuretic peptide (BNP) levelssurrogate

Endothelial cell damage and dysfunction are present in congestive heart failure and are independently associated with the condition alongside BNP.

Cite This Study

Chong et al. (2004) studied this question.

synapsesocial.com/papers/6a70b40e22b3175134db55da https://doi.org/10.1161/01.cir.0000143073.60937.50

Topics

Heart failure HFrEF treatment

View Full Paper

Ask AI

Bookmark

Endothelial Dysfunction and Damage in Congestive Heart Failure

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Endothelial Dysfunction and Damage in Congestive Heart Failure

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider