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December 1, 1964Proceedings of the National Academy of SciencesOpen Access

The Cardiac Calcium Pump

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Authors

MCMary E. CarstenUniversity of California, Los Angeles

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Implication

Highlights potential targets in diastolic dysfunction; leaves open translation of molecular mechanisms to clinical interventions.

Key Points

  • To examine the structural, biochemical, and physiological mechanisms governing the cardiac calcium pump and its role in cardiac muscle function.
  • Synthesis of molecular and physiological literature concerning calcium transport mechanisms within cardiac tissue.
  • Delineates the enzymatic regulation of calcium transport across the sarcoplasmic reticulum membrane.
  • Identifies the key regulatory interactions modulating pump activity during the myocardial contraction and relaxation cycle.

Cite This Study

Mary E. Carsten (1964) studied this question.

synapsesocial.com/papers/6a70b6038031ec7bb1dc853dhttps://doi.org/10.1073/pnas.52.6.1456
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Role of Calcium in the Mechanism of Relaxation of Cardiac Muscle1964 · 138 citations
  2. 2PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT1951 · 318,728 citations