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Integrative multi-level modeling from genetics to whole-organ physiology is essential for understanding cardiac arrhythmias and preventing drug-induced proarrhythmic side effects.
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
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Denis Noble (2002) studied this question.
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