Why the study?
Does transgenic expression of the mouse salivary gland renin gene alter pressure-diuresis-natriuresis relationships in rats?
Does transgenic expression of the mouse salivary gland renin gene alter pressure-diuresis-natriuresis relationships in rats?
Transgenic rats expressing the mouse renin gene exhibit a rightward shift in the pressure-natriuresis relationship, suggesting enhanced tubular reabsorption contributes to their hypertension.
No takes yet. Share an insight, caveat, or question.
Does not support changing hypertension management; leaves open whether tubular reabsorption drives human disease.
Groß et al. (1994) studied this question.
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