Why the study?
Does the level of systolic blood pressure control affect hospitalizations and mortality in elderly black patients with systolic-diastolic hypertension?
Does the level of systolic blood pressure control affect hospitalizations and mortality in elderly black patients with systolic-diastolic hypertension?
In elderly black hypertensive patients, partial control of systolic blood pressure (mean ~151 mm Hg) is associated with lower rates of hospitalization and mortality compared to both inadequate and complete control, suggesting a J-curve effect where control should not be too rigorous.
May caution against both inadequate and intensive SBP control in elderly Black hypertensives; leaves open optimal targets pending randomized confirmation.
To study what effect the level of control of systolic blood pressure (SBP) has in elderly persons with systolic-diastolic hypertension, 503 elderly black hypertensive patients were followed up for as long as nine years. The combined rate of hospitalizations and mortality for hypertension-related disorders was significantly (P less than 0.01) higher for the group with inadequate control of SPB (mean, 183.6 mm Hg) than for the group with partial (mean, 151.2 mm Hg) or complete (mean, 131.5 mm Hg) control. The group with complete control of SBP had a significantly (P less than 0.005) higher combined rate of hospitalizations and mortality for hypertension-related disorders than did the group with partial control. This suggests that a target goal for control of systolic as well as diastolic blood pressure should be set for elderly black hypertensive patients. However, the control of SBP should not be to rigorous.
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Applegate et al. (1982) studied this question.