Systemic Inflammation and Oxidative Stress in Childhood Obesity: Sex Differences in Adiposity Indices and Cardiovascular Risk

Figure 1. Boxplots of selected inflammation and oxidative stress biomarkers in girls stratified by BMI percentile (pBMI). p-value annotation legend: ns: Not significant (p > 0.05), *: Significant (0.01 < p ≤ 0.05). CRP—c-reactive protein, WBC—white blood cells/leukocytes, MPO—myeloperoxidase, MCP-1—monocyte chemoattractant protein-1, ADPN—adiponectin, I-TAC—interferon-inducible T-cell alpha chemoattractant.

Figure 2. Boxplots of selected inflammation and oxidative stress biomarkers in boys stratified by BMI percentile (pBMI). p-value annotation legend: ns: Not significant (p > 0.05), *: Significant (0.01 < p ≤ 0.05). CRP—c-reactive protein, WBC—white blood cells/leukocytes, MPO—myeloperoxidase, MCP-1—monocyte chemoattractant protein-1, ADPN—adiponectin, I-TAC—interferon-inducible T-cell alpha chemoattractant.

Figure 3. Heatmap for inflammation/oxidative stress parameters in correlation to adiposity indices, laboratory parameters, blood pressure and pulse wave velocity. Positive correlations are represented by shades of red, while negative correlations are indicated by shades of blue. Because of several correlations, BH correction was performed. Inflam/OS—overall inflammation and oxidative stress, ADPN—adiponectin, MCP-1—monocyte chemoattractant protein-1, MPO—myeloperoxidase, I-TAC—interferon-inducible T-cell alpha chemoattractant, CRP—c-reactive protein, WBC—white blood cells/leukocytes, BMI—body mass index, WC—waist circumference, HC—hip circumference, WHtR—waist-to-height ratio, WHR—waist-to-height ratio, VFT—visceral fat thickness, SFT—subcutaneous fat thickness, FFM—fat-free mass, TBW—total body water, ECW—extracellular water, BCM—body cell mass, FM—fat mass, PA—phase angle, TSH—thyroid-stimulating hormone, T3—triiodothyronine, T4—thyroxine, Hb—hemoglobin, FG—fasting glucose, AST—aspartate aminotransferase, ALT—alanine aminotransferase, GGT—gamma-glutamyl transferase, TB—total bilirubin, TC—total cholesterol, LDL—low-density lipoprotein, HDL—high-density lipoprotein, TGC—triglycerides, Lp…