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April 1, 1997Antimicrobial Agents and ChemotherapyOpen Access

Emergence of an inhibitor-resistant beta-lactamase (SHV-10) derived from an SHV-5 variant

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Authors

EPE.E. PrinarakisVMVivì MiriagouΕTΕva Tzelepi

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Prinarakis et al. (1997) studied this question.

synapsesocial.com/papers/6a70ba69febe604dd7097febhttps://doi.org/10.1128/aac.41.4.838
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Inactivation of class A .beta.-lactamases by clavulanic acid: the role of arginine-244 in a proposed nonconcerted sequence of events1993 · 138 citations
  2. 2Role of the conserved amino acids of the ‘SDN’ loop (Ser130, Asp131 and Asn132) in a class A <i>β</i>-lactamase studied by site-directed mutagenesis1990 · 110 citations
  3. 3OHIO-1 β-lactamase resistant to mechanism-based inactivators1992 · 35 citations
  4. 4Clinical isolates of <i>Escherichia coli</i> producing multiple TEM mutants resistant to β-lactamase inhibitors1994 · 44 citations
  5. 5SHV-5, a novel SHV-type beta-lactamase that hydrolyzes broad-spectrum cephalosporins and monobactams1989 · 117 citations