Answers are grounded in this paper and cite their sources.
Case report demonstrates favorable clinical outcome following interferon-alpha combination therapy in hypereosinophilic restrictive cardiomyopathy, highlighting its therapeutic potential.
The idiopathic hypereosinophilic syndrome is characterized by a prolonged overproduction of eosinophils of unknown cause in addition to specific organ damage due to eosinophil-derivated protein toxicity. Its prognosis is correlated with heart involvement that results in a restrictive cardiomyopathy. This is frequently biventricular. Isolated left ventricular infiltration has rarely been reported. The authors report a case of idiopathic hypereosinophilic syndrome with cardiac involvement obliterating the left ventricular cavity with a favorable clinical outcome following a combination therapy with interferon-alpha, hydroxyurea and prednisone. Data from other studies dealing with the treatment of idiopathic hypereosinophilic syndrome with interferon-alpha are reviewed and discussed.
No takes yet. Share an insight, caveat, or question.
Baratta et al. (2002) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: