Extensive surgery including bilateral ventricular endomyomectomy and valve replacements can provide significant short-term improvement in patients with severe hypereosinophilic heart disease.
May support extensive surgery in refractory hypereosinophilic heart disease; leaves open durability and generalizability.
A 45-year-old patient with cardiac involvement from the idiopathic hypereosinophilic syndrome suffered from severe congestive cardiac failure with progressive deterioration despite intensive medical therapy. Investigations indicated bilateral ventricular infiltration with endomyocardial fibrosis which had caused severe haemodynamic restriction and bilateral atrioventricular valvular incompetence. Extensive surgery, which included bilateral ventricular endomyomectomy and mitral and tricuspid valve replacements, resulted in a significant improvement for six months.
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Cameron et al. (1985) studied this question.
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