Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
March 1, 2001AJP Renal Physiology

NHERF: targeting and trafficking membrane proteins

View Full Paper
Ask AI
Bookmark
Share

Design

Review

Authors

SSShirish ShenolikarDuke UniversityEWEdward J. WeinmanUniversity of Maryland, Baltimore

Discussion

Loading...

Member takes

Implication

NHERF modulation may influence renal Na+ handling; leaves open its validation as a therapeutic target in hypertension or volume disorders.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Shenolikar et al. (2001) studied this question.

synapsesocial.com/papers/6a70bc318031ec7bb1dc8abahttps://doi.org/10.1152/ajprenal.2001.280.3.f389
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1NHERF Associations with Sodium−Hydrogen Exchanger Isoform 3 (NHE3) and Ezrin Are Essential for cAMP-Mediated Phosphorylation and Inhibition of NHE32000 · 138 citations
  2. 2Functional characterization of three isoforms of the Na+/H+ exchanger stably expressed in Chinese hamster ovary cells. ATP dependence, osmotic sensitivity, and role in cell proliferation.1994 · 261 citations
  3. 3Separate C-terminal Domains of the Epithelial Specific Brush Border Na+/H+ Exchanger Isoform NHE3 Are Involved in Stimulation and Inhibition by Protein Kinases/Growth Factors1995 · 128 citations
  4. 4Dopamine inhibits Na(+)-H+ exchanger activity in renal BBMV by stimulation of adenylate cyclase1990 · 210 citations
  5. 5cAMP-independent regulation of CFTR by the actin cytoskeleton1995 · 92 citations