It all adds up: A chiral La(OTf)3/N,N′-dioxide complex has been developed for the asymmetric direct Michael addition of nitroalkanes to nitroalkenes. This reaction afford 1,3-dinitro compounds with two stereocenters in good yields with high diastereo- and enantioselectivity (up to d.r. 93:3, 97 % ee; see scheme, Tf=trifluoromethanesulfonyl) under mild conditions.
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Xu et al. (2008) studied this question.
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