March 1, 1997Cardiovascular ResearchOpen Access

The capillarity of left ventricular tissue of rats subjected to coronary artery occlusion

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Population

Ethylether-anesthetized and ventilated rats

Design

Preclinical

Follow-up

30 days

Authors

ZXZhiping XieShanghai Jiao Tong University MGMingchun GaoShanghai University SBSanjay BatraSouthern University and Agricultural and Mechanical College

Discussion

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Implication

Angiogenesis-hypertrophy mismatch in rat transition zone; leaves open relevance to human post-MI remodeling.

Structured PICO

Population

Ethylether-anesthetized and ventilated rats

Intervention

Left coronary artery occlusion with a thin suture

Outcome

Capillarity of left ventricular tissue (assessed via morphometric analyses including cross-sectional area of cardiomyocytes, capillary to myocyte ratio, total capillary density, and capillary domain area)surrogate

In a rat model of chronic coronary occlusion, capillary angiogenesis fails to keep pace with myocyte hypertrophy in the transition zone surrounding the infarct over 30 days.

Cite This Study

Xie et al. (1997) studied this question.

synapsesocial.com/papers/6a70bd255d37378ac1dde186 https://doi.org/10.1016/s0008-6363(96)00250-7

View Full Paper

Ask AI

Bookmark

The capillarity of left ventricular tissue of rats subjected to coronary artery occlusion

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The capillarity of left ventricular tissue of rats subjected to coronary artery occlusion

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider