What question did this study set out to answer?

This research aims to identify optimal timing and assess long-term survival outcomes following primary heart valve replacement.

January 1, 1997European Journal of Cardio-Thoracic SurgeryOpen Access

Long-term relative survival after primary heart valve replacement1

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Why the study?

What is the long-term relative survival of patients undergoing primary heart valve replacement compared to the general population?

Population

2365 patients who underwent their first heart valve replacement

Comparison

Primary heart valve replacement vs Expected survival among persons from the general…

Design

Cohort

Follow-up

10 years

Authors

ESElisabeth StåhleCardiac Surgery PKPer KvidalUppsala University Hospital SNS-O NyströmUppsala University

Discussion

Member takes

Implication

Supports valve replacement in older or less symptomatic patients with survival nearing population norms; extends long-term outcome data but leaves optimal timing open for prospective study.

Key Points

This research aims to identify optimal timing and assess long-term survival outcomes following primary heart valve replacement.
Analyzed the survival of 2365 patients undergoing their first heart valve replacement.
Compared observed survival rates to expected rates in the general Swedish population, stratified by age and sex.
Utilized a multivariate model with the Cox proportional hazards model to evaluate survival predictors.
Early mortality rates were 5.9% for aortic, 10.4% for mitral, and 10.6% for combined replacements.
Ten-year relative survival rates were 84% after aortic, 68.5% after mitral, and 80.9% after both types.
Factors influencing late survival included age, NYHA class, and aortic regurgitation post-replacement.

Structured PICO

What is the long-term relative survival of patients undergoing primary heart valve replacement compared to the general population?

Population

2365 patients (1568 without and 797 with concomitant coronary artery bypass grafting [CABG]) who underwent their first heart valve replacement

Intervention

Primary heart valve replacement (aortic, mitral, or combined aortic and mitral)

Comparator

Expected survival among persons from the general Swedish population stratified by age, sex, and 5-year calendar period

Outcome

Early mortality (within 30 days) and relative survival rates at 10 yearshard clinical

In patients ≥70 years or those with mild/no symptoms, long-term survival after primary aortic or mitral valve replacement is similar to the general population.

Cite This Study

Ståhle et al. (1997) studied this question.

synapsesocial.com/papers/6a70c317ac440176ef296bc4 https://doi.org/10.1016/s1010-7940(96)01025-1

Topics

Valvular heart disease

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Implication

Supports valve replacement in older or less symptomatic patients with survival nearing population norms; extends long-term outcome data but leaves optimal timing open for prospective study.

Long-term relative survival after primary heart valve replacement1

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Long-term relative survival after primary heart valve replacement1

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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