Why the study?
Pulse transit time is a key index of cardiovascular health status and CVD diagnosis, prompting the development of a novel image analysis-based method for its estimation using equivalent time sampling.
A novel equivalent time sampling-based method for post-processing color Doppler videos can successfully estimate pulse transit time, flow average velocity, and pulse wave velocity in experimental phantom models.
May support image-based PTT estimation from Doppler videos; leaves open clinical validation before diagnostic use.
The increasing incidence of cardiovascular diseases (CVDs) is reflected in additional costs for healthcare systems all over the world. To date, pulse transit time (PTT) is considered a key index of cardiovascular health status and for diagnosis of CVDs. In this context, the present study focuses on a novel image analysis-based method for PTT estimation through the application of equivalent time sampling. The method, which post-processes color Doppler videos, was tested on two different setups: a Doppler flow phantom set in pulsatile mode and an in-house arterial simulator. In the former, the Doppler shift was due to the echogenic properties of the blood mimicking fluid only, since the phantom vessels are non-compliant. In the latter, the Doppler signal relied on the wall movement of compliant vessels in which a fluid with low echogenic properties was pumped. Therefore, the two setups allowed the measurement of the flow average velocity (FAV) and the pulse wave velocity (PWV), respectively. Data were collected through an ultrasound diagnostic system equipped with a phased array probe. Experimental outcomes confirm that the proposed method can represent an alternative tool for the local measurement of both FAV in non-compliant vessels and PWV in compliant vessels filled with low echogenic fluids.
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Fiori et al. (2023) studied this question.
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