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November 1, 2002Journal of Biological ChemistryOpen Access

Synthetic Smac/DIABLO Peptides Enhance the Effects of Chemotherapeutic Agents by Binding XIAP and cIAP1 in Situ

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Authors

CAChristina R. ArntMayo ClinicMCMihnea V. ChioreanMayo ClinicMHMichael P. HeldebrantMayo Clinic

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Arnt et al. (2002) studied this question.

synapsesocial.com/papers/6a70c716ac440176ef296fbdhttps://doi.org/10.1074/jbc.m207578200
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Generation and Characterization of Smac/DIABLO-Deficient Mice2002 · 174 citations
  2. 2Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative–(BMS 247550) and Apo-2L/TRAIL–induced apoptosis2002 · 163 citations